Context-dependent activation of STING-interferon signaling by CD11b agonists enhances anti-tumor immunity

CD11b agonists offer a novel approach for treating lupus nephritis

Cover Feature: A Genetic Model of Constitutively Active Integrin CD11b/CD18 

Positive Allosteric Modulation of CD11b as a Novel Therapeutic Strategy Against Lung Cancer

Cover Feature: Agonism of CD11b reprograms innate immunity to sensitize pancreatic cancer to immunotherapies

Integrin CD11b activation drives anti-tumor innate immunity

Leukadherin-1 ameliorates endothelial barrier damage mediated by neutrophils from critically ill patients

CD11b Activity Modulates Pathogenesis of Lupus Nephritis

CD11b activation suppresses TLR-dependent inflammation and autoimmunity in systemic lupus erythematosus

Integrin Cross-Talk Regulates the Human Neutrophil Response to Fungal β-Glucan in the Context of the Extracellular Matrix: A Prominent Role for VLA3 in the Antifungal Response

Leukadherin-1 Attenuates Hyperoxia-induced Lung Injury in Neonatal Rats

A Small Molecule β2 Integrin Agonist Improves Chronic Kidney Allograft Survival by Reducing Leukocyte Recruitment and Accompanying Vasculopathy

Agonist leukadherin-1 increases CD11b/CD18 dependent adhesion via membrane tethers

Small molecule agonists of integrin CD11b/CD18 do not induce global conformational changes and are significantly better than activating antibodies in reducing vascular injury

Complement receptor 3 influences Toll-like receptor 7/8 dependent inflammation: implications for autoimmune diseases characterized by antibody reactivity to ribonucleoproteins

Small molecule-mediated activation of the integrin CD11b/CD18 reduces inflammatory disease

High-throughput screening based identification of small molecule antagonists of integrin CD11b/CD18 ligand binding

Identification of novel agonists of the integrin CD11b/CD18

A simple, no-wash cell-adhesion based high throughput assay for the discovery of small molecule regulators of the integrin CD11b/CD18

Toward the development of podocyte-specific drugs

High-content screening assay-based discovery of paullones as novel podocyte-protective agents

Stop that podocyte!

Cover Feature: A Podocyte-Based Automated Screening Assay Identifies Protective Small Molecules